产品货号:
Z27698
中文名称:
SRCIN1抗体
英文名称:
Anti-SRCIN1 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-SRCIN1 Antibody |
| 指标别名 | SRC kinase signaling inhibitor 1;P140;SNIP;SRCIN1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | SRCIN1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from the Internal region of human p140Cap.at AA rangle:780-860 |
| 计算分子量 | 112KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | Immunogen affinity purified |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
| 背景资料 | Using yeast 2-hybrid analysis,protein pull-down assays,and mutation analysis,it is showed that the first coiled-coil domain of rat Snip interacted with the N-terminal t-SNARE domain of Snap25 (600322).Biochemical studies demonstrated that Snip was tightly associated with rat brain cytoskeleton.Indirect immunofluorescence and confocal microscopy of rat PC12 pheochromocytoma cells revealed colocalization of Snip with Snap25 in the actin cytoskeleton,particularly in filopodia,lamellipodia,and neuritic extensions,including the tips.Overexpression of Snip or its Snap25-interacting domain inhibited calcium-dependent exocytosis from PC12 cells.It is concluded that SNIP is involved in regulation of neurosecretion,perhaps via its interaction with SNAP25 and the cytoskeleton. |
| Uniprot ID | Q9C0H9 |
| 基因名全称 | SRC kinase signaling inhibitor 1 |
| 推荐稀释比 | WB,1:500~1:2000 |
相关搜索:SRCIN1抗体,SRCIN1多抗,Anti-SRCIN1 Antibody
